We use the word 'hope' perhaps more often than any other word in the vocabulary: 'I hope it's a nice day.' 'Hopefully you're doing well.' 'So how are things going along? Pretty good. Going to be good tomorrow? Hope so.'
What can you do if a part of it is uphill? You can't work out another route. You've just got to run the one they give you. But they tell me London is a nice course. Even the cobbles I hope are not very much of a problem for me.
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Now science has presented us with a hope called stem cell research which may provide our scientists with many answers that have for so long been beyond our grasp.