The main environmental challenge of the 21st century is poverty. When you don't know where your next meal is coming from it's hard to consider the environment 100 years down the line.
Without international participation jobs and emissions will simply shift overseas to countries that require few if any environmental protections harming the global environment as well as the U.S. economy.
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In the rich world the environmental situation has improved dramatically. In the United States the most important environmental indicator particulate air pollution has been cut by more than half since 1955 rivers and coastal waters have dramatically improved and forests are increasing.