If you're lucky enough to be involved in a film that's about something very real and that you hope will continue to hold up in 20 years' time it just gives you more energy and makes it feel all the more worthwhile.
What can you do if a part of it is uphill? You can't work out another route. You've just got to run the one they give you. But they tell me London is a nice course. Even the cobbles I hope are not very much of a problem for me.
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Now science has presented us with a hope called stem cell research which may provide our scientists with many answers that have for so long been beyond our grasp.