If you are a great dramatic actor then you often don't know if people are enjoying your stuff at all because they are sitting there in silence. But with comedy it's a simple premise. If it's funny people laugh. If it's not they don't.
It's painful for me to watch someone who isn't funny. It's horrifying to sit in the back and watch some guy who just totally sucks.
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The surprising thing is that I was not funny in high school. I was always jealous of the funny kids because they always got the girls. I couldn't tell a joke to save my life.