I think most artists would be happy to have bigger audiences rather than smaller ones. It doesn't mean that they are going to change their work in order necessarily to get it but they're happy if they do get it.
It's not the destination that matters. It's the change of scene.
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Physics does not change the nature of the world it studies and no science of behavior can change the essential nature of man even though both sciences yield technologies with a vast power to manipulate the subject matters.