A man can stand a lot as long as he can stand himself. He can live without hope without friends without books even without music as long as he can listen to his own thoughts.
What can you do if a part of it is uphill? You can't work out another route. You've just got to run the one they give you. But they tell me London is a nice course. Even the cobbles I hope are not very much of a problem for me.
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Now science has presented us with a hope called stem cell research which may provide our scientists with many answers that have for so long been beyond our grasp.