A good actor is someone who knows how to take the part and make it real and make it honest and be effective in it. If it's in a funny movie and as long as they are cast in an appropriate way humor will come from it.
Probably it is impossible for humor to be ever a revolutionary weapon. Candide can do little more than generate irony.
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I think I've learned that if you want to be successful you have to tell your story honestly and from your heart – and I think a healthy sense of humor doesn't hurt either.