The mind controls so much of the body. We are much more than flesh and blood we are complex systems. Patients do better when they have faith that they're going to do better. That's why I always tell my patients and their families not to neglect their prayers. There's nobody I don't say that to.
If faith is lost there is no security and there is no life for him who does not adhere to religion.
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My gut feeling about sequels is that they should be premeditated: You should try to write a trilogy first or at least sketch out a trilogy if you have any faith in your film.