If those committed to the quest fail they will be forgiven. When lost they will find another way. The moral imperative of humanism is the endeavor alone whether successful or not provided the effort is honorable and failure memorable.
A man is rich in proportion to the number of things he can afford to let alone.
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Just as a cautious businessman avoids investing all his capital in one concern so wisdom would probably admonish us also not to anticipate all our happiness from one quarter alone.